![]() ![]() Significant gender differences appeared in that females were more likely to suffer from comorbid anxiety disorders, have a history of sexual trauma, and be HIV positive whilst men were more likely to have a forensic- and substance-abuse history, experience hallucinations and receive clozapine. It was found that two-thirds of study subjects had consulted with faith- or traditional healers. ![]() Treatment choice appeared to be a combination of a mood-stabilising agent in combination with an anti-psychotic. ![]() The high rates of attempted suicide, history of violence and history of drug abuse all furthermore points to the devastating effects bipolar disorder has on individuals and their families. The study also confirms the debilitating nature of bipolar disorder with more than two-thirds being unemployed in spite of a quarter of the study subjects having a tertiary education. This study confirms that a unipolar manic course is indeed much more common than rates suggested in present day literature with 57% of the study sample only ever experiencing manic episodes. A purposeful sample of 103 patients was recruited and interviewed using the Affective Disorders Evaluation. This was a descriptive, cross-sectional study of patients presenting with a history of mania between October 2009 and April 2010, to three hospitals in Limpopo Province. The purpose of this study was to investigate and describe the course of illness and clinical features in a cross-section of patients diagnosed with bipolar disorder attending public hospitals in Limpopo Province, South Africa and to determine the rate of a unipolar manic course in this sample of patients. In literature, a unipolar manic course of illness in particular is reported to be rare. Abstract There is generally a lack of studies examining prevalence and phenomenology of bipolar disorder in Africa. ![]()
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